The blood transfusion is an essential part of modern medical care. Used properly can save lives. Throughout the world, the centers that make blood products strive to provide safe of them, since the process of the transfusion could be without risks. At this point is essential the rational use of the same, imposing the need to balance the benefits and potential side effects that could produce like allergic and hemolytic reactions, metabolic processes, effects on cellular immunomodulation, lung damage or transmission of infectious diseases (HIV, HBV and HCV, among others). For More biomedical open access journals;

