β-HCG as a Tumor Biomarker with Special Reference to Breast Cancer | Human chorionic gonadotropin (HCG) is a placental protein hormone initially secreted by cells (syncitiotrophoblasts) from the implanting conceptus. It supports the ovarian corpus luteum, endometrial lining and consequently maintains pregnancy [1]. The hormone can be detected in blood and urine, as it is the basis of many pregnancy tests. HCG plays many other roles including stimulating the onset of fetal gonadal steroidogenesis, promotion production of corpus luteal progesterone, immuno-suppression and blockage of phagocytosis of invading trophoblast cells, cytotrophoblast differentiation, growth and differentiation of fetal organs [2]. It is well known that a biomarker is any molecular and chemical changes that can be measured and used to study normal or abnormal process in the body. A tumor marker, like a biomarker, is a naturally occurring substance in the body. A tumor marker can be made by cancer cells or by the body in response to cancer. Tumor markers can provide information that can be used to screen and diagnose cancer as well as identify the stage of cancer to monitor a treatment. For More Articles: Journal of Biomedical Research and Reviews : https://biomedres.us/

Ascitic Type of Abdominal Tuberculosis in a 40 Year Old Female | Disseminated tuberculosis can cause a lot of damage to an individual if there is no early diagnosis. In Africa, about 70% of patients with abdominal tuberculosis present with ascites and most of these cases are missed diagnostic cases. The case in question is of a 40 year old women from one of the rural areas of Zimbabwe who had previously presented with severe coughing but had denied sweating at night and the sputum results were negative on screening. After 2 weeks she presented again at the clinic with a swollen abdomen and the X-ray showed flooding of the lungs and difficulty in breathing. Disseminated tuberculosis can cause a lot of damage to an individual if there is no early diagnosis. In Africa, about 70% of patients with abdominal tuberculosis present with ascites and most of these cases are missed diagnostic cases [1,2]. The patient presents with a swollen abdomen containing many litres of strawcoloured fluid. The fluid accumulates as the result of large numbers of miliary tubercles on the peritoneum. The only certain way to make the diagnosis is to do a minilaparotomy (‘’minilap’), which will also enable you to diagnose cirrhosis, peri portal fibrosis (due to Schistosomiasis mansoni), carcinomatosis of the peritoneum and hepatoma (usually with cirrhosis). Experts can usually diagnose miliary tuberculosis with their naked eyes; but even they can be wrong, so take a biopsy of his parietal peritoneum and/or his liver. [3] The case in question is 40year old women from one of the rural areas of Zimbabwe who had previously presented with severe coughing but had denied sweating at night and the sputum results were negative on screening. For More Articles: Scientific Research Articles on Biomedical : https://biomedres.us/

Hemophagocytic lymphohstiocytosis: A Case Report | Hemophagocytic lymphohistiocytosis (HLH) is a life threatening hyper inflammatory syndrome occurring due to ineffective immune process. It can be genetic (familial form) or secondary (acquired form). We present a case of HLH in a 50 year old male who presented with pancytopenia and huge platelet clumps on peripheral smear which subsequently leads to diagnosis after correlation with clinical, hematological and biochemical findings. Hemophagocytic syndrome with special mention to its secondary form is a rare syndrome which occurs after strong immunologic activation and release of cytokines characterized by unrestricted activation of T lymphocytes and macrophages invariably leading to death in absence of treatment [1,2]. It is associated with certain clinical and hematological abnormalities of which pancytopenia, hyper ferritinaemia, hepatosplenomegaly, fever and hemophagocytosis in bone marrow were observed in our case. For More Articles: Biomedical Journal Articles : https://biomedres.us/

Follicular Dendritic Cells Sarcoma in Accessory Salivary Glands | Follicular Dendritic cells sarcomais a relatively rare entity with intermediate malignancy. Their evolution is characterized by the frequency of local and/or remote relapses. Due to their rarity, the treatment is not consensual in the literature. We report a rare case of follicular dendritic cells sarcoma of accessory salivary glands in a 45-year-old patient whose progression is favorable after surgery followed by chemo-radiotherapy and review of the literature. Follicular Dendritic cellstumors are rare entities (less than 1% of malignant salivary gland tumors). Only a few cases have been reported in the literature [1-2]. In addition to their rarity, these tumors shows difficulties in the diagnosis of certainty and in the optimal the rape utic strategy. We report an exceptional case of follicular dendritic cell sarcoma of submaxillary accessory salivary glands in a 45-year-old man and discuss the therapeutic strategy based on data from the literature. For More Articles: Biomedical Open Access Journals : https://biomedres.us/

Methomyl-Induced Acute Poisoning in Industrial Workers: Five Case Reports | To understand the poisoning and mechanism of methomyl. To collect the data of occupational history, case data, auxiliary examination and so on, and to present the diagnosis results of occupational diseases in the occupational disease diagnosis group of methomyl. Methomyl was detected in the working environment in 2 cases. The patients have a clear history of exposure to the drug, with a typical carbamate pesticide poisoning symptoms. Occupational exposure to methomyl can cause occupational poisoning. This paper analyzed five cases of acute methomyl poisoning to provide information for the prevention and control of occupational poisoning by methomyl. For More Articles: Journal of Scientific and Technical Research : https://biomedres.us/

When Angiography Makes a Difference – Polyarteritis Nodosa- A Rare Cause of Mid- Gastrointestinal Bleeding | We present a case of overt and recurrent mid-gastrointestinal bleeding with hemodynamic repercussion and severe limitation to the patients’ quality of life, followed in our department for the last 6 years. The final diagnosis of isolated gastrointestinal involvement of Polyarteritis Nodosa was only reached after multiple hospital admissions, imaging and gastroenterological examinations. A subtle finding of micro aneurysms in the mesenteric circulation opened the way to effective treatment when endoscopic treatment had failed to prevent recurrences. Mid gastrointestinal bleeding (MGIB) is uncommon but represents the majority of cases of recurrent GI bleeding without an obvious source, even after endoscopic and imaging evaluation [1]. Overt MGIB manifestations depend on the rate of bleeding and when associated with hemodynamic instability may present with haematemesis, melaena and/or haematochezia. For More Articles: Biomedical Science Articles : https://biomedres.us/

Ecosystem Services of Insects | Insects comprise the most diverse group of multicellular organisms in the planet Earth, which provide several ecosystem services like pollination, pest control (bio-control), decomposition, transference of energy through food chain etc. In addition, insects are widely used today as human edible items and ingredients of fish-feed, turtle-feed, livestock, etc. In this paper we focus on the vital ecosystem services provided by insects with special reference to their services in the domain of human food. Our research stands on the high nutritional value of insects preferably protein which ranges between 13% – 77%. Our paper has two-fold goals namely documentation of selective ecosystem services of insects and highlighting the edible value of insects. In this paper we have intentionally excluded the value of commercially produced insectderived products like honey, wax, silk, shellac, etc. rather our main focus is to highlight the nutritional value of insects which is the most demanding subject to feed the rapidly rising population in the present world. For More Articles: Biomedical Research Articles : https://biomedres.us/

Fine structure of Somatotrophs in Pars Distalis of the Indian wild Caught Female Bat, Taphozous nudiventris kachhensis (Dobson) | The ultra structural observations on Somatotrophs During estrus cells are spherical to oval in shape with the spherical nucleus. Cytoplasm of cell is filled with a large number of round to oval shaped secretory granules of diameter ranges from 200-400nm. Cells during early pregnancy are polyhedral in shape with eccentric nucleus and mostly euchromatic. Mitochondria are spherical to oval in shape with lamellar cristae. The Golgi zone is observed juxtanuclear in position. Secretory granules are increases in number as compared to estrus. STH cell during lactation are polyhedral in shape. Rough endoplasmic reticulums are elongated, tubular dotted with ribosomes. Secretory granules are seen scattered in the cytoplasm. The diameter of secretory granules is about 230 nm. For More Articles: Biomedical Science Articles : https://biomedres.us/

The Effect of Alcohol Intoxication on Mortality in Road Traffic Injury Patients at Level I Apex Trauma Centre in India | Alcohol consumption arising as leading risk factor for road traffic injuries and one of the major public health concerns globally. Alcoholism is associated with liver disease, coronary vascular disease, Hypertension, Stroke, acute pancreatitis etc. [1-4]. There has been a rapid change in recent years towards alcohol use in India and originated as one of the main contributors to health problems. Recent studies have demonstrated that drink driving is strongly associated with a higher frequency of road traffic accidents which leads to hospitalization to emergency department. The alcohol use is increasing in urban areas, therefore, injuries related to alcohol intake and driving is also increased like road traffic accidents, fire and burns, pedestrian falls and drowning as well as intentional injuries such as violence against oneself or others. In developing countries, like India, alcohol related injuries are matter of concern due to the resource constraint setting as burden of injuries have huge impact on the overall economic growth of the country andmajor part of the GDP is lost due to road traffic injuries. For More Articles: Biomedical Research Articles : https://biomedres.us/

Effect of Season on In-vitro Anti Oxidant Activity of Astilberivularis Buch – Ham. Ex D. Don leaves | Effect of season on in vitro anti oxidant activity of Astilberivularis Buch. – Ham. Ex D. Don leaves was studied. Leaves of Astilberivularis Buch. – Ham. Ex D. Don were collected in different seasons and in vitro anti oxidant activity of the leaves was measured by superoxide anion generation with the help of xanthine-xanthine oxidase assay and with linoleic acid peroxidation assay as well as by DPPH photometric assay. Total phenol, flavonoids, ascorbic acid and carotenoid contents in the leaves of different seasons were also estimated. Results showed that in vitro anti oxidant activity of the leaves of Astilberivularis Buch. – Ham. Ex D. Don was found maximum during rainy season (June – July). Anti oxidant compounds in leaves like total phenol, flavonoids, ascorbic acid and carotenoids were also present in maximum amount during rainy season. Anti oxidant activity, therefore, was related with high content of total phenol, flavonoid, ascorbic acid and carotenoids in the leaves. Leaves of Astilberivularis Buch. – Ham. Ex D. Don of rainy season should be used to get maximum anti oxidant activity. For More Articles: Journal of Biomedical Research and Reviews : https://biomedres.us/