Diurnal Effect of Selenium Supplementation on Adult Female Wistar Rats made Hypothyroid by Methimazole | Diurnal variation in gastric emptying is known to affect the bioavailability of ingest. The present study sought to understand the effect of consumption of selenium in daytime or nighttime on some clinical features of hypothyroidism in female wistar rats. 36 adult female wistar rats weighing 120-150g were randomly divided into 6 groups: vehicle-treated, methimazole, daytime – selenium, nighttime-selenium, methimazole+ daytime-selenium and methimazole+ nighttime selenium groups. Hypothyroidism was induced through oral administration of 1.35mg/kg body weight of methimazole. 7mg/ml of Selenomethionine was administered through drinking water for two weeks. When compared with vehicletreated group, methimazole administration caused a significant (P<0.05) decrease in caudal cold tolerance (CCT) and Body Temperature (BT). Rats administered selenium during day-time showed a significantly higher (P<0.05) plasma glucose and decreased CCT. Nighttime selenium administration to hypothyroid rats resulted in a significant decrease (P<0.05) in plasma glucose. There was an insignificant change in CCT and BT in hypothyroid rats administered selenium in day-time. In conclusion, the study showed that daytime selenium consumption may exert more positive influence on hypothyroidism than nighttime selenium consumption. For More Articles: Scientific Research Articles on Biomedical : https://biomedres.us/

Medically Compromised Dental Patient: Dentists Nightmare | Present day advances in medical sciences and technology has resulted in substantial increase in the volume of dental patients with systemic illnesses. The term Medically Compromised refers to dental patients with impaired health status like pregnancy, or patients with systemic diseases like ischemic heart disease, congenital heart disease, liver disease, renal disease, asthma, patients with immunodeficiency and patients with altered immune status. Search of literature showed a paucity of data regarding prevalence of medical diseases and conditions among the dental patients. Absence or inadequacy of precautions needed to be taken while carrying out routine dental treatment in these patients may result in worsening their medical status or even result in a fatality. Care needs to be taken while prescribing medications for these patients in the form of altered dosage or altering the medications themselves. Medico-legal litigations are reportedly on the rise in all the countries across the globe due to increased patient activism and awareness of their rights and sensationalization of such cases by the media. For More Articles: Biomedical Journal Articles : https://biomedres.us/

Nutriepigenomics Advances into Personalized Nutrition | This review presents an omics systems perspective that presents an integrated approach to understanding the contribution of the genetic, epigenetic, metabolomic, and proteomic interactions under the influence of a dynamic nutritional environment. The review takes into account the application of genomic and post-genomic era methodologies being used to study the impact of inter-individual phenotypic differences and disease susceptibility to current and future generations. Every individual alive today is a combination of the heliotypes inherited from their parents, and the results of genetic-epigenetic interaction influencing the fetal epigenome during pre-natal development and post-natal life. Epigenetic marks imprinted in-utero are attributed to deficits in the maternal contribution to the fetal nutritional environment. Integral to this discussion is the concept of developmental plasticity, which presents itself as an unfolding narrative in the “developmental origins of health and disease” (DOHaD) hypothesis, and the ‘predictive adaptive response (PAR)’ concept. When taken together, these concepts present the case for an adaptive response to developmental programming that canpredispose an individual to future diseaseor confers an advantage. Nutriepgenomics is the study of how nutrients affect human health through epigenetic modifications. Recent advances investigating how the nutritional environment during embryonic development influences the establishment of metabolic phenotypes that can contribute to the emergence of disease are discussed. Several encouraging trials suggest that prevention and therapy of age- and lifestyle-related diseases by individualized tailoring to optimal epigenetic diets including combinations of natural products, polyphenols or drugs are conceivable. For More Articles: Biomedical Open Access Journals : https://biomedres.us/

(Croatian, World) Soils – Between Food and Non-Food Functions and Ownership Relations | Summarizing “global soil inventory” through published books of World Soil Book Series of A. Hartemink there are recognizable two tendencies in global Soil sciences. One of them, just respecting importance of environment – regulatory (“non – food”) functions of soil, like soil scientists of Europe and developed countries expect to see the future of Soil science within environmental sciences. They insist on soil monitoring and “green energy” and more or less accept soil (land) as essential resource of (environmentally, socially economically) sustainable production of biofuels. The other one, productive function of soil – (food) oriented, see Soil science within agriculture and forestry, insisting on ever-higher yields of growing crops and forest. For More Articles: Biomedical Journal Articles : https://biomedres.us/

Antibacterial Potential of Argemone mexicana Solvent Extracts against Neisseria | Gonorrhea is a sexual transmitted infection which is caused by Gram negative bacteria called Neisseria gonorrhoea (gonococcus). N. gonorrhoea is inherently susceptible to most antibiotics, but through continual usage, resistance has emerged. Plants employ antimicrobial activity of phytochemicals as a protection mechanism against pathogens. It is due to this activity that phytochemicals have landed themselves into the medical field as potential solutions to a rapidly increasing drug resistant spawn of microorganisms. There is an increased multiple antimicrobial resistant patterns in N. gonorrhoea due to continual use of specific antibiotics, foreign plasmid acquisition and genetic evolution. Emergence of multidrug resistant strains of the pathogen poses a threat and thus the need to seek alternative medicine. For More Articles: Biomedical Journal Impact Factor : https://biomedres.us/

Exploring the Big Five Factor Traits of College Going Adolescents | Personality generally refers to the way of responding to the external demands. This study tries to explore the Big Five Factor traits among students of different disciplines. Implications have been raised by giving propositions for future researchers to validate these propositions. For More Articles: Scientific Research Articles on Biomedical : https://biomedres.us/

Creating a Healthier Nation through Public Health Genetics | The US Surgeon General Family History Initiative is a powerful tool enabling individuals of the general population to engage in preventive health care as they proactively make well informed decisions regarding the quality of their overall well-being. Knowing which healthy as well as hazardous genes are present in their karyo types will empower individuals to transform their lives in order to decrease the onset of preventable illnesses and/or lessen the severity of disease manifestations. Reading through the website of the US Surgeon General Family History Initiative will reveal to the general population that both the manifestations of physical and behavioral disorders may demonstrate familial transmission as they afflict the well-being of biological relatives living during various generations. For More Articles: Journal of Biomedical Research and Reviews : https://biomedres.us/

Emotional and Behavioral Problems | Behavioral difficulties are a complex and very serious issue as their manifestation is not only due to genetic and neurological factors but also to the interaction children have with the environment where they live. A child’s problematic behavior may be associated with the “bad” family environment they live in as well as the bad relationships they have with their family. Whether there are no ties of love between parents and their children, or they neglect them, or they do not show appreciation and respect, or they abuse them, and generally they do not praise them or they do not pay attention to their skills, it is very likely that these children develop problematic behaviors because of the grief and sadness they feel. A problematic behavior can be displayed either in an aggressive or antisocial way or with depression and frustration. Both internal and external problem behavior include isolation from the community and a negative identity. Firstly, a key asset for the teacher is to create a relationship of trust with the child, to stress their positive characteristics and emotional skills, to encourage them to have a good image and appreciation for themselves, to create cooperation and communication ties between the teacher and the child as well as between the classmates and the child with problematic behavior, so that children could feel that they do not have a negative identity, that they are no different from the other classmates and especially could avoid any exclusion and isolation may have. For More Articles: Biomedical Research Articles : https://biomedres.us/

Emerging Infectious Disease and Transfusion Medicine: Time to take Action with Proactive Measures | One of the concerns throughout the history of transfusion medicine has been the transmission of infectious diseases through the transfusion of allogeneic blood. Since the identification of post transfusion hepatitis in the 1940s [1], the AIDS epidemic in the 1980s [2], the discovery of hepatitis C in 1989 and its role in blood donation and transmission of HCV [3], and most recently -between 1980 and 1996 the delivery of the variant of Creutzfeldt- Jakob disease by blood transfusion [4,5], transfusion medicine had to implement stronger and more secure measures in the selection of blood donors and in the diagnosis of Transfusion-transmissible diseases (TTD) in order to avoid post-transfusion transmission of infectious agents, mainly HBV, HCV and VIH. For More Articles: Biomedical Journal Articles : https://biomedres.us/

When Liquid Biopsy Cell-Free DNA Meets with Tissue Biopsy RNA | The human genome contains ~30,000 genes that need to be expressed in specific cells at precise times. The DNA in the nucleus exists in two forms that reflect the level of activity of the cell. Through electronic microscopy, heterochromatin appears as small, darkly staining, irregular particles scattered throughout the nucleus or accumulated adjacent to the nuclear envelope; on the other hand, euchromatin is dispersed and not readily stainable. Euchromatin comprises the most active portion of the genome within the cell nucleus and is enriched in genes, and is often under active transcription, whereas non-coding sequences are most abundant in heterochromatin. The position in the chromosome and/or changes to the chromatin structure can significantly influence gene expression: genes are usually silenced when the chromatin is condensed, and are active when chromatin is open. These dynamic chromatin states can be regulated at multiple levels via reversible epigenetic patterns of DNA methylation, histone or nucleosome modifications as well as tissue-specific transcriptional activators and repressors. For More Articles: Biomedical Open Access Journals : https://biomedres.us/