Efficient Way to Use Whey as Ready to Serve (RTS) Beverage |

Abstract

Whey is the largest by product of huge dairy industry and is one of the most troublesome byproduct produced. Whey based beverages with different concentrations of fruit juices and standard ingredients of Ready to Serve (RTS) beverage can be prepared. Ready to drink beverages offer the advantages of convenience and portability to today’s busy consumers. Utilization of whey for the conversion into best beverage would be one of the important ways to utilize it. Nutritive value of whey may be increased by the addition of some simple ingredients. Whey proteins are often the preferred source for ready-to-drink protein beverages because of their excellent nutritional qualities, bland flavor, ease of digestibility, and unique functionality in beverage systems.

Introduction

Utilization of whey produced during the manufactures of cheese, paneer, channa and shrikhand has been of great concern. In India, it is estimated that about 100 million kg of whey is annually derived as a byproduct which may cause substantial loss of about 70,000 tonnes of nutritious whey solids [1]. Whey, a valuable dairy by product contains half of the milk solids and is a rich source of lactose, water soluble vitamins, minerals, and immunologically active proteins [2]. It contains about 50-55% total milk solids, 70% of milk sugar, 20% of milk proteins and 70-90% of minerals and almost all water soluble vitamins especially vitamin B complex and vitamin C [3]. Whey proteins consist of lactoferrin, lactoperoxidase, βlactoglobulin, α-lactalbumin, bovine serum albumin, thermostable fractions of proteose peptones, immunoglobulins and bioactive peptides. Presence of essential amino acids such as lysine, cysteine, methionine and cystin imparts anticarcinogenic properties to these proteins [4].

For More Articles: Journal of Scientific and Technical Research : https://biomedres.us

Human and Animal Thermophilic Campylobacter infections in East African countries: Epidemiology and Antibiogram |

Abstract

Purpose: Campylobacter mediated diarrhoea is a leading cause of gastroenteritis worldwide. The organisms colonize the gastrointestinal tract of different animal species without causing disease symptoms. Humans acquire infections through contact with or consumption of contaminated meat especially raw/undercooked poultry meat. The rapid emergence of antibiotic-resistant Campylobacter strains heightens the public health concern of the organisms. The aim of this review was to summarise information on the epidemiology and antibiogram of Campylobacter in humans and animals in East African countries.

Method: A structured literature search of PUBMED and Science Direct electronic databases.

Results: Forty reports on thermophilic Campylobacter were identified in four of the five East African countries in the following order; Kenya (16), Tanzania (17), Uganda (4) and Rwanda (3). No study was found to report thermophilic Campylobacter infections in either humans or animals in Burundi. Studies on animals reported colonization of both domestic and wild species. Of the studies that described Campylobacter infections in humans, both symptomatic and asymptomatic subjects were reported to be infected; with higher prevalence in subjects younger than five years old. Among isolates, some demonstrated antimicrobial resistance.

Conclusion: Available information for both human and animal Campylobacteriosis in the region is however sparse thus calling for more research to better understand the epidemiology of infections caused by the organism including clonal dependence and independence of human and animal derived isolates. This understanding will help researchers and health program developers in designing and implementing effective control strategies. Since the organism is zoonotic its control strategies should adopt the “One Health” approach involving collaborative efforts from veterinary and human medicine.

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The Lifespan of Humans and Animals Can Be Significantly Extended |

Opinion

The averagelifespan of animals varies greatly from a few days to hundreds of years. The Antarctic sponge CinachyraAntarctica has lived for 1550 years, the ArcticaIslandica clam for more than 400 years. The longest-living vertebrate is the Aldabra giant tortoise (Aldabrachelysgigantea), which can live for more than 200 years. The longest-living mammal is the bowhead whale (Balaenamysticetus) (up to 200 years). Another long-live mammal is an elephant, who lives up to 70 years. People in more economically developed countries normally live for 80 years, but there is a group of people over the age of 100 years. We can also find enormous lifespan differences among birds. The golden eagle (Aquila chrysaetos) lives up to 80 years, the large parrots Ara up to 70 years old, while the small songbirds live 5-10 years.

The shortest life has a mayfly (Ephemeroptera) (1-3 days), unless we don’t count the time when the mayfly was a nymph. The short-live mammals are rats (2-4 years) and hamsters (2-3 years). In the animal kingdom the rule is that larger animals live longer, but this rule has a number of exceptions. The purebred dogs make one of the exceptions where, on the contrary, dogs of higher weight live shorter life.

It is very likely that the secrecy of longevity is determined in genes. The information about how long will the animal live is written in the genome of all animals. This information is specific and different for each species. It was formed during hundreds of millions of years of evolution and is determined to provide the best conditions for the survival of the species, not the survival of the individual.

Today we are at the beginning of the process of identifying and analysing genes responsible for longevity. The first genes related to longevity have already been discovered in mice and humans. Once our knowledge of genes responsible for longevity is expanded, it is realistic to imagine the possible use of this knowledge to significant extension of the lifespan of humans and animals.

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To Operate or Not to Operate: The Dilemma between Surgery versus Conservative Management of Cervical Disc Herniation |

History and Physical Examination

A 49 year old male commercial airline pilot presented to the PM&R spine clinic for an “epidural steroid injection”. The patient complained of neck pain radiating to his left posterolateral arm, and to the 4^th and 5^th digits occasionally. Symptoms began 28 days earlier, and involved waking up in pain, without any history of injury. He described his neck and radiating arm pain as sharp and constant, with an intensity range of 2-8/10. Symptoms were exacerbated by neck movement, while cervical traction and tramadol alleviated the pain temporarily. He also had occasional numbness/tingling of the left 4^th and 5^th digits. The patient was otherwise healthy. The patient was employed as a commercial airline pilot but was on medical leave due to the severity of his symptoms. Due to the nature of his profession and the concern for the safety of passengers, he was not allowed to go back to work until his condition improved. Physical examination was significant for left deltoid atrophy and subtle shoulder abduction weakness. Spurling’s maneuver caused radiating pain to the left posterolateral arm at the elbow level. Neck range of motion was decreased due to pain.

Imaging Studies

His primary care physician had requested a cervical spine MRI without intravenous contrast (Figure 1). The most significant finding was a C6-C7 disc bulge (Arrows) with a superimposed moderate-sized left paracentral disc herniation with superior extrusion, which contacted the left anterolateral aspect of the cervical cord and impinged on the exiting left C7 nerve root.

Clinical Decision Making

The clinical decision was between continuing conservative care or surgical intervention. Conservative care would have consisted of physical therapy and a cervical epidural steroid injection, using either a transforaminal or an interlaminal approach. In deciding which treatment option to pursue, we considered the following factors: the large size of herniated nucleus pulposus (NP), the severity of the spinal canal stenosis (Figure 1A & 1B), the risk of further spinal cord compression and neurological consequences, and the patient’s occupation. Owing to the nature of his symptoms, including weakness and atrophy of muscles, the patient was referred for surgery. These listed impairments directly affected the patient’s work, and we wanted to prevent further deterioration or permanent impairment. A surgical consultation was requested and tramadol was prescribed for pain control.

Surgical Approach

Four days later, the patient was evaluated by a neurosurgeon and was promptly recommended for C6-C7 anterior cervical discectomy and interbody fusion utilizing a fibular allograft. Surgery was performed 10 days after the patient’s initial visit to the PM&R clinic. The C6-C7 disk space was distracted with a vertebral body spreader. The disk was then removed using a high-speed drill. In dissecting the posterior ligament off the dura, a large free fragment of herniated disk was identified and removed, to decompress the dural sac completely. Foraminotomies were performed bilaterally at C6-C7, to provide complete decompression of exiting nerve roots. The C6 and C7 endplates were decorticated and the intervertebral space was filled with allogeneic fibular bone fragments. A metal plate was then contoured between C6 and C7 and two screws were inserted into C6 and C7 respectively, to stabilize the two motion segments.

A 49 year old male commercial airline pilot presented to the PM&R spine clinic for an “epidural steroid injection”. The patient complained of neck pain radiating to his left posterolateral arm, and to the 4^th and 5^th digits occasionally. Symptoms began 28 days earlier, and involved waking up in pain, without any history of injury. He described his neck and radiating arm pain as sharp and constant, with an intensity range of 2-8/10. Symptoms were exacerbated by neck movement, while cervical traction and tramadol alleviated the pain temporarily. He also had occasional numbness/tingling of the left 4^th and 5^th digits. The patient was otherwise healthy. The patient was employed as a commercial airline pilot but was on medical leave due to the severity of his symptoms. Due to the nature of his profession and the concern for the safety of passengers, he was not allowed to go back to work until his condition improved. Physical examination was significant for left deltoid atrophy and subtle shoulder abduction weakness. Spurling’s maneuver caused radiating pain to the left posterolateral arm at the elbow level. Neck range of motion was decreased due to pain.

For More Articles: Journal of Scientific and Technical Research : https://biomedres.us

The Most Common Discomfort |

Mini Review

The present work refers to one of the discomforts that most affect the human organism: stress; it provides a definition of the term, the main hormones that are secreted and their effects, as well as some of the damage that can cause the human body that affect their internal balance and therefore their well-being.

Where does the word stress come from?

The term stress (from the Latin stringere ‘squeeze’) and its derivative in English stress (fatigue of material) arises from the investigations carried out by Hans Selye in the 1930s, who from the studies carried out to different patients determined that regardless of the disease they suffered, their symptoms coincided with fatigue, weight loss, appetite, frequent fatigue, physical and psychic weakness. The word stress comes from physics, science that is in charge of the study of energy, matter, time and space, in this case refers to the pressure exerted by one body on another, and the one that receives the most pressure can shatter. Selye’s studies later led to the conclusion that stress is the nonspecific response to any demand to which the organism is subjected, to which he refers in his research entitled “Stress” published in 1950.

What is stress?

From the search in different bibliographic sources of what stress means we can say that it consists of a response given by the organism, can be positive or negative to a situation caused by factors coming from both the external or internal environment and can affect homeostasis. Positive stress is one that favors the body, that is, it allows solving a certain situation and adapting to the new conditions. Negative stress breaks the internal balance of the body (homeostasis) Causing Anxiety, Fatigue, Anger, Exhaustion and Irritability.

What are the major hormones secreted in the face of stress?

The consequences of stress impact on mood and health. In this situation several hormones are involved but the main ones are: adrenaline and cortisol. The first is responsible for giving us that fast momentum that we need. In a matter of moments, our energy goes up enormously to help us escape the danger, as a result breathing becomes faster and increases the heart rate so that the muscles respond more quickly, prevents blood clots, blood circulates more quickly, experience physical sensations such as tightness in the chest, palpitations, cold sweating, tingling in the stomach.

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Study of Chondrosarcoma in Northwest Region of Libya |

Abstract

Chondrosarcoma (CS) is a relatively rare malignant tumor of chondroblasts with pure hyaline cartilage differentiation. The neo-plastic cells do not synthesize osteoid, but areas of calcification, ossification and myxoid change may be seen. A total of 14 cases were obtained from two major hospitals in the northwest region of Libya over a period of 6 years. Clinico-pathological data were evaluated including age and gender. The result showed that (CS) was slightly more common in females than in males, male to female ratio was (1.7: 2) with a peak incidence in the second and third decades of life. It is concluded from this study that CS is generally a slightly more common in females than in males and more frequently affected patients in the second and third decades of life. There is no any previous published article regarding this aspect in the northwest region of Libya. Therefore, this paper may will bring forward data for further study of CS in future in Libya.

Introduction

Chondrosarcoma is a rare malignant tumor of chondroblasts with pure hyaline cartilage differentiation. The neo-plastic cells do not synthesize osteoid, but areas of calcification, ossification and myxoid change may be seen. Chondrosarcoma is the third most frequent primary malignant tumor of bone exceeded only by myeloma and osteosarcoma. It usually occurs in the trunk bones (pelvic girdle, shoulders, ribs) followed by the femur and humerus [1,2]. Chondrosarcomas may be divided in two major categories, central chondrosarcoma (primary or conventional), which arise in the medullary canal and then perforate the cortical plate and surface chondrosarcomas which arise on the bone surface and grow into the adjacent soft tissue, known as peripheral Chondrosarcomas either periosteal or juxtacortical Chondrosarcoma. In addition to central and surface Chondrosarcomas, some pathologists further subdivide Chondrosarcoma into primary which occur de novo and secondary Chondrosarcoma that occur in a preexisting lesions, as well as another three variants of Chondrosarcomas that have distinctive histological features, clear cell Chondrosarcoma, mesenchymal Chondrosarcoma and dedifferentiated Chondrosarcoma.

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Contamination of Frozen Broiler Chicken Meats with Antimicrobial Resistant Thermophilic Campylobacter in Morogoro, Tanzania |

Purpose: Majority of the human bacterial gastroenteritis cases in both developed and developing countries in the world are caused by thermo tolerant Campylobacter spp, with C. jejuni and C. coli being more involved. These bacteria live in poultry and other animal’s intestinal tracts without causing disease symptoms. Improper handling of carcasses during slaughter and evisceration increases the chance of contaminating the outer skin. Poor meat handling in the kitchen and poor storage during refrigeration causes cross contamination. Contamination of Frozen Broiler Chicken Meats with Antimicrobial Resistant Thermophilic Campylobacter in Morogoro, Tanzania.

Methods: This cross-sectional study examined the occurrence of antimicrobial resistant thermophilic Campylobacter in frozen chicken meats in Morogoro Municipality. A total of 272 frozen broiler chicken carcasses were obtained from supermarkets (n=90), meat shops (n=90) and restaurants (n=92). Each carcass was divided into three parts i.e. breast, thighs and wing+neck, rinsed in peptone water. The rinses were then enriched in 5ml of Bolton broth in microerophilic atmosphere at 42ºC for 24hrs. Then the broth was streaked on Modified Charcoal Cefoperazone Deoxycholate Agar (mCCDA) plates followed by incubation at 42ºC for 48 hrs. Presumptive colonies of Campylobacter spp. were sub cultured onto Mueller Hinton Agar and incubated at 42ºC for 48 hrs to obtain pure colonies. Pure Campylobacter colonies were then subjected to preliminary identification using biochemical tests and further confirmed by polymerase chain reaction (PCR). Antimicrobial Susceptibility testing was performed on C. Jejuni isolates by disc diffusion method on Mueller-Hinton agar supplemented with 5% of horse blood. The isolates were tested for resistance against ten antimicrobials namely tetracycline, gentamycin, ciprofloxacin, azithromycin, erythromycin, norfloxacin, chloramphenical, amoxicilin, nalidixic acid and cephalocin.

Conclusion: This study confirms that in our setting a high frequency of commercial broiler chickens are positive for antimicrobial resistant Campylobacter at the time of slaughter. This phenomenon derives in high contamination of carcasses during the slaughter process thereby constituting a substantial public health hazard. Freezing of carcasses does not completely remove this bacterium as seen from this study. Control strategies for these pathogens at flock level are recommended to avoid contamination of the final product. Animal products should be properly handled and thoroughly cooked in order to make sure that safe products are consumed.

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Probiotics for Health Benefits: The Regulatory Concerns and Suggestive Roadmap | Probiotics, the friendly bugs, has gained impressive attention worldwide due to their nutraceutical and pharmaceutical benefits, established in recent years. However existing regulatory regime in various countries has ambiguities regarding its classification based on intended use and respective approval process. Author and his coworkers have proposed a revised definition and categorization of probiotic products along with possible path to develop a comprehensive guideline for global enactment. For More Articles: Biomedical Journal Articles : https://biomedres.us

Interpreting Maternal Death: When Underlying Causes Are Non-Medical Despite Medical Indications | The relationship between the medical caregiver and the patient usually displays an authoritative knowledge [1,2] of the former although the latter contributes to making the health care delivery more efficient [3]. Despite an involvement of the patient, his/her embodied knowledge [4] most often lacks legitimacy considering the health service delivery procedures particularly in the presence of a complication. However, the prominence of the patient’s subjective interpretation may contribute to challenging the practice of the biomedicine regarding the accountability in some context. The following reflection draws on two cases of maternal death that occur in Ouenkoro’s community health centre, a rural area in central Mali. The health facility is the first level of health care delivery in the Malian health systems. The midwife in charge of providing child birth services has been running the maternity for about thirty years. In the two cases highlighted the context of care delivery waschallenged by the parturient subjective interpretations of their conditions. Those accounts not only gained legitimacy over the clinical indications but also in reporting the maternal deaths from the perspective of the midwife. Interpreting Maternal Death: When Underlying Causes Are Non-Medical Despite Medical Indications. For More Articles: Biomedical Open Access Journals : https://biomedres.us

Hypersensitivity to Intravenous Ondansetron | A 33 year old male who was recovering after cholecystectomy presented a sudden onset of breathing difficulty and rashes all over the body with inj. Andtron (Ondansetron -4mg). The condition progressed to cardio pulmonary arrest, which was fortunately resuscitated successfully. Ondansetron is a highly potent antiemetic drug that is effective in preventing postoperative nausea and vomiting with very low risk of adverse reactions. We are reporting a reaction that is probably due to an allergy to serotonin blockers (Ondansetron, Granisetron). The patient recovered on discontinuing the drug and with appropriate treatment. Hypersensitivity to Intravenous Ondansetron. For More Articles: Journal of Scientific and Technical Research : https://biomedres.us